A Shocking Triple Kill

Renekton's E-skill was avoidable, but the stun effect from his W landed after she had released her arrow, so Vayne couldn't deal much damage during the time that she was stunned.

Using life steal, Vayne was able to recover some of her health and she now had one-third of health, and Renekton who was pure tank couldn't possibly kill Vayne now. Every third arrow shot from her bow gave an additional eight percent true damage of the target's maximum health, and even Renekton who had a lot of health would eventually die without Randuin's Omen.

Vayne chased Renekton from the bottom brush all the way to the Dragon's Pit, and he was now left with a third of his health. Going against a Vayne who had her essential items, being a meat tank was basically useless. With one-third of her health bar remaining, all Vayne needed was two shots of Silver Bolts' bonus true damage, and the gigantic crocodile could only die there and then.