The Ice Seal Potion is a very niche potion; its effect is to create an ice-seal effect on the user, temporarily relieving the user's injuries and pain, buying some crucial treatment time for patients with severe external injuries. However, this potion is rarely used in hospitals because it is very difficult to refine, and general pharmacists do not attempt to make it.
Guding had actually refined this potion before, and the solution was simple. It only required adding a type of animal oil called Sea Saliva Fragrance to the potion, which had to be mixed with Ice Blue Grass Extract before the refining process. This little method is also a part of the Pharmacist Civilization that had been lost, yet it is clearly recorded in Sea Emperor's database.