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Clive McKay chose two mice of different ages, one about a month old and the other sixteen months old. He cut their bodies open, used medical techniques to connect key capillaries, forming a complete circulatory system to ensure that blood could flow. After some time, he would cut them open again to revert back to their normal configuration.
After the surgical suturing, he continued to observe the growth condition of the two mice and made detailed records. The content of these records included heart rate, metabolism, and other various indicators.
After observing the mice for a month, he discovered that the older mouse appeared to be rejuvenating and showed signs of reduced physiological age.
Following this, many biologists conducted similar experiments, eventually concluding that blood transfusions could reverse aging and thus extend lifespan.