But Bellito also knows that AstraZeneca brought related drugs (osimertinib) to cooperative laboratories in other countries on the grounds of cooperating with clinical trials. This is the company's private behavior, and they really can't say. what.
After all, AstraZeneca is a multinational pharmaceutical company, not just a US pharmaceutical company.
Bellito's department can only issue warnings, fines and other measures to AstraZeneca, but what's the use?
Bellito called the team angrily, and he was going to AstraZeneca's headquarters in person!
Xia State, Chang Zezhou.
Qu Ping placed a box of Osimertinib in front of Chen Xiao.
Chen Xiao had seen this medicine before.
Before the rebirth, Chen Jinsong, the grandfather of the parallel universe Chen Xiao, suffered from lung cancer and took this medicine.
At that time, this drug was not localized, and there was no cooperation agreement with AstraZeneca to introduce it, so Chen Xiao could only buy it from the United States at a high price through personal relationships.
At that time, 1,700 yuan per tablet (80mg), one tablet a day, cost up to 51,000 yuan a month.
Fortunately, Chen Xiao's economic conditions are good and he can afford it.
Grandpa did extend his life for several years through this medicine.
But Chen Xiao knew very well that there were thousands of people in Xia who couldn't afford this medicine and could only wait to die in bed.
Later, the country introduced the drug to the United States through negotiation, and the price was reduced to 510 yuan per piece. The cost of taking osimertinib for a month was 15,300 yuan. After reimbursement by medical insurance, the patient's monthly cost was 4,590 yuan.
This price is much cheaper than a few years ago, but it is still very expensive for many Xia people.
Especially around 2020, nearly 43% of Xiaguo's households have a per capita monthly income of less than 1,090 yuan, 56.5% of the population's per capita monthly household income is less than 1,500 yuan, and 69% of the population's per capita monthly household income is less than 2,000 yuan. In other words, the per capita monthly income of most people in the country is less than 2,000 yuan.
This kind of medicine, which is as high as 4,590 yuan per month, is unaffordable even if it is reimbursed by medical insurance.
Therefore, seeing such a medicine, Chen Xiao still sighed.
Chen Xiao said to Qu Ping, "Send the medicine to the medical team to see how to treat He Jiang."
Osimertinib has a good effect on brain metastases from lung cancer, so even if He Jiang's lungs have been removed, there are still brain metastases and kidney metastases.
There is absolutely no problem with using this drug.
Chen Xiao added: "Some of the drugs are sent to the laboratory, and Asan can prevent them. We optimize the drugs on the basis of imitation, and there should be no problem in evading their patented technology."
"By the way, let's inform both the Shanghai Stock Exchange and Yanjing, so that they won't be in a hurry."
Chen Xiao also saw the media reports about He Jiang's condition and the lack of medicine in the past few days.
The reason why the relevant media reported the incident at this point in time was that they did not hold any hope for He Jiang's treatment.
Qu Ping immediately did as Chen Xiao said.
In Yanjing, Xie Fei received a call from Changtian Technology and was informed that osimertinib had been used in He Jiang's clinical treatment.
After getting this news, Xie Fei was stunned!
Xie Fei used all available private and public relations, but he didn't get the medicine, and the other party's response was very tough.
These Xie Fei recognized it!
Who says their country's medical technology is inferior to that of the United States?
If you fall behind, you will be beaten. This has always been the case since ancient times.
He did not expect that Changtian Technology would get the medicine so easily.
And it's a guaranteed supply.
Xie Fei asked relevant insiders in detail what was the reason for Changtian Technology to get Osimertinib.
Xie Fei was even more shocked when he learned that Changtian Technology required many pharmaceutical companies to supply products immediately at the expense of business in the Americas!
You know, Changtian Technology is just a private company.
A private company does not need to require the other party to have a great sense of national, national and historical responsibility. After all, the other party wants to make money and eat.
In order to be able to buy medicines, Xie Fei approached many state-owned pharmaceutical companies that had business dealings with AstraZeneca. But the other party was either incompetent or afraid of damaging the relationship with AstraZeneca, so he made various excuses to avoid it.
Only Changtian Technology can stand up at the first time, and use its own business of hundreds of millions of yuan every year as a bargaining chip to negotiate with the other party.
And Xie Fei knew very well that this matter had nothing to do with Changtian Technology.
He Jiang suffered from small cell lung cancer, not pulmonary fibrosis or other severe lung diseases. Changtian Technology Intensive Care Center is not a professional hospital for cancer treatment.
However, Changtian Technology is still obliged to stand up and complete such a arduous task.
Xie Jiang felt very uncomfortable!
Fortunately, Changtian Technology is a technology company of Xia Guo, not a company from the United States or Toyo.
If Changtian Technology is an overseas company, what a terrible competitor it must be!
Xie Fei immediately sat in front of the computer, wrote a report in person, and reported the relevant situation of Changtian Technology's acquisition of Osimertinib to the above.
Such companies must be given significant policy and economic support conditions.
Xie Fei even felt that relying on state-owned research institutes to conquer anti-cancer drugs like osimertinib was definitely hopeless, and he could only rely on Changtian Technology.
Xie Fei had spent time in state-owned research institutes, and he was the same as doing more and less, and his slackness was quite serious.
Under such circumstances, only fools will have the spirit of scientific research and innovation, and it is true that they can do less work and make more money. Who will really make efforts in scientific research?
Xie Fei knows this situation too well!
On the contrary, Changtian Technology is more dynamic than many state-owned research institutes.
The news that Changtian Technology had obtained the drug was quickly known by the media, and many media who had been following He Jiang's follow-up situation came to Changtian Technology to verify whether they had obtained osimertinib.
In the past few days, a large number of reporters are either crowded in the reporter reception room of the intensive care center, or they are frantically calling Changtian Technology for verification.
Seeing that the reporters were so enthusiastic, Qu Ping held a brief press conference only after seeking Chen Xiao's opinion in order to ensure the normal working order of the treatment center.
"Hello Director Qu, has Changtian Technology tried to get Osimertinib?"
"Director Qu, a reporter from the National Radio and Television Station, Xu Tao. How did Changtian Technology get osimertinib, and has the drug been used for the treatment of Chief Engineer He?"
"Director Qu, I'm a reporter from Xinlang.com. As far as we know, AstraZeneca has prohibited the sale or gift of Osimertinib to any country, individual or organization in the world. How did Changtian Technology get it? drug? What is the current treatment effect of this drug?"
In fact, this time Qu Ping organized this press conference, and was very upset.
When is it all?
The medical team of the intensive care center was trying to save the patient's life, but the reporter on this side was concerned about how the medicine came from.
Qu Ping did not look good, and said: "The reporters have asked a lot of questions, so I will not answer them one by one. The medicine was brought back by Changtian Technology through certain efforts, and the treatment is currently in progress. I hope that the reporters can give the treatment team. For a certain period of time, it will also give Chief He a quiet treatment environment."
After Qu Ping gave a simple answer, the reporters at the scene cheered and applauded, discussing excitedly.
"Changtian Technology still has a way!"
"That's right, a lot of departments have tried all kinds of ways, but they haven't gotten Yaochangtian Technology and it's done as soon as it comes out."
"The medicine is easy to handle! The effect should be very powerful. I have seen some experimental data from AstraZeneca. Osimertinib has a very good effect on lung cancer metastasis to the brain."
Qu Ping was quite surprised.
The reporters were applauding.
Whether it is Chen Xiao or Qu Ping, they all feel that it is shameful for the people of Xia to go abroad to seek medicine. What the **** are these people applauding?
Celebrate each other handing out a little cancer drug to you?
Qu Ping squeezed her hands, and said with a bad face: "I don't think it's a matter of pride for so many scientific research institutions and pharmaceutical companies in my country to be unable to produce corresponding anti-cancer drugs. Today's press conference is here. Here, thank you all."
After Qu Ping dropped these words, she left the conference room, leaving behind the reporters who looked at each other in dismay.
The reporters also blushed, and suddenly felt that what Qu Ping said was very reasonable.
What are you excited about?
So happy because of a little charity from a Western company?
The medicine was not produced by Xia Guo, nor was it bought through normal trade, what is there to be happy about?
Looking at the back of Qu Ping's departure, the reporters suddenly gained some profound understanding of Changtian Technology's views.
They felt that this private company was different from the companies they had known before.
In the past, especially some hospitals or scientific research centers, if they also encountered He Jiang's incident, they would also do everything possible to buy osimertinib from AstraZeneca.
That must be rushing to hold a press conference, rushing to take credit, thinking that being able to buy drugs from AstraZeneca is a great virtue, and it must be a big report, and even a medal of merit.
The approach of Changtian Technology is completely different from them.
This time, Changtian Technology has almost single-handedly overwhelmed its medical industry in the state of Michigan, so that the pharmaceutical giants in the United States can compromise and get the relevant drugs.
But Changtian Technology never felt that this was a merit, but a particularly shameful thing.
Because Xia Guo's technology company is not strong, there is no way to rely on its own ability to produce anticancer drugs comparable to osimertinib.
Because Xia Guo is not strong enough, we have many research institutes, and scientific research funds are quite generous, but we don't even have a pharmaceutical company to replace AstraZeneca.
The idea has put many journalists to shame.
"Changtian Technology hopes that anti-cancer drugs will no longer be purchased abroad!" After half an hour, Xinlang reported the entire content of the interview with Changtian Technology's press conference on the headline on the front page.
The content of the report basically restored the whole process of the press conference. At the end of the report, the commentator of Xinlang exclaimed:
"Changtian Technology was not excited because it broke through all obstacles and purchased osimertinib, but was frustrated because no domestic pharmaceutical company could produce anti-cancer drugs similar to osimertinib!
We hope that more scientific research companies in Xiaguo will stand up, and we hope that the next time we need comparable drugs, a technology company in Xiaguo can provide domestically produced drugs as quickly as possible, instead of trying every means to seek Therefore abroad. "
Not only heart waves, but many media reporters who participated in the Changtian Technology Conference had a different feeling.
The heart waves that followed one after another reported the relevant situation.
Netizens also felt very surprised when they saw this conference of Changtian Technology.
Because Changtian Technology can get osimertinib through its own way, which is already a very remarkable thing.
However, Changtian Technology did not take credit and pride as everyone imagined, but felt guilty for not being able to develop similar drugs.
This kind of pursuit of excellence in science and technology is exactly what many scientific research institutions in Xia Guo lack.
Fei also saw the relevant media reports, and he silently took a sip of tea.
This is the scientific research company that Xia Guo needs.
He Jiang's condition stabilized after treatment.
But no one can guarantee that the tumor will not spread or metastasize.
We can only hope that after the condition stabilizes, the lesions will gradually shrink and eventually disappear.
After He Jiang completed the combined colony transplantation and lung resection, he was able to sit on the bed and speak softly.
This time, Chen Xiao and Qu Ping went to visit him, and it happened that the leaders of the 606 Institute and colleagues were there.
He Jiang's students and subordinates held notebooks and listened to every explanation from He Jiang.
He Jiang said: "Although our engine can be installed on the aircraft, there are still some defects."
"One is that the temperature in front of the vortex reaches 1500k, and the efficiency will be reduced by 10%. The other is that if the thrust is added, the fuel efficiency will be reduced to 60%, and it will not reach our combat radius of 1200-1500km. Our design thrust is 17 tons, The actual thrust is less than 12 tons."
"I... My latest data shows..." He Jiang gasped heavily.
"Teacher, don't worry, speak slowly."
The students quickly handed the water to He Jiang.
After He Jiang had his lungs removed, he relied on the thoracic diaphragm to make his voice, so the voice sounded strange and difficult.
He Jiang took a sip of water, then slowed down after a while, and said, "Currently, the 10-year overhaul of the turbofan is less than 1,000 hours, and the use efficiency is too low..."
"Because of technical reasons~www.mtlnovel.com~ we have not been able to match the thrust vectoring nozzle..."
The students stopped He Jiang's words and were very disappointed.
They all thought that Turbofan 10 had been successful through decades of research, but did not expect that there are so many details. The students knew about these things before, but they were repeatedly reminded by He Jiang on this occasion, which made everyone feel uncomfortable.
At this time, Chen Xiao said: "The turbofan-10 adopts a three-stage fan, nine-stage rectifier, one-stage high pressure, and one-stage low pressure, which is the so-called 3+9+1+1 structure with high thrust, high thrust-to-weight ratio and low bypass ratio. engine."
"However, with the current thrust, if the vector nozzle is equipped, not only will it not be able to speed up urgently, but it will easily lead to a stall. The reason is that the thrust is still insufficient."
When Chen Xiao said this, everyone turned around.In the eyes of everyone in the 606 Institute, Chen Xiao can easily tell the structure and some parameters of the turbofan 10 engine, which is very surprising.
Because the turbofan 10 engine has been "quasi" successfully developed at present, but after all, it is not equipped on the aircraft, and no information has been released to the public. How did Chen Xiao know?
Everyone looked at He Jiang again, thinking that this was some data revealed by He Jiang when he was chatting with Chen Xiao these days.
Chen Xiao touched his nose and forgot about this mess.
However, he saw that these people in the 606 Institute had been illegal, so he was a little impatient.
After all, He Jiang's physical condition is there, and what he needs most now is recuperation. It's better to talk less and have a good rest.
Chen Xiao said: "The biggest difficulty at present is to make the temperature in front of the vortex withstand more than 1700 ℃, so that the maximum fuel efficiency can be exerted. In addition, we also need to use better materials and technologies to make the engine compressor withstand the pressure. Above 50 atmospheres, while maintaining these two premises, the centrifugal force on the blade tip is at least more than 50 tons."
Chen Xiao said this, and everyone in the 606 Institute became quiet.
Every word of Chen Xiao got to the point. Everyone felt that Chen Xiao should understand the engine.
Because the most critical engine is actually the three words "high temperature, high pressure, high speed".
These three words, if they are taken out individually, are very simple, and each of them is very technically handled.
For example, the engine of a launch vehicle can withstand ultra-high temperatures.
But the rocket's engine is bulky and can only be used once.
Another example is the rotor of a large mechanical equipment. The speed is very high, and the volume can be made infinitely large, which increases the load of the rotor.
But it is very difficult to integrate into aero-engines.
Because aero-engines are required to be small in size, light in weight, long in life, and reusable, this is very difficult.
Therefore, aero-engines are known as the pearls of human industry and the most exquisite products in industrial design.
A colleague from the 606 Institute listened to Chen Xiao for a long time. At first, he thought it made sense. Then, when he heard the back, he felt that Chen Xiao was a little unreasonable.
Because Chen Xiao only mentioned some of the difficulties the engine is currently facing, but did not say any solutions.
Everyone knows the difficulties faced by the engine. This can only prove that Chen Xiao has an understanding of the engine, and it does not prove that he can solve the problem.
A researcher named Liu Dagen from the 606 Institute said: "We also know that the turbofan 10 engine will face these difficulties. The temperature in front of the vortex cannot reach above 1700 ℃. Everyone knows this problem, but how can we solve this problem?"
Even if there is no way to solve these problems, the turbofan 10 engine can be forcibly loaded on the j11 body, but some subsequent flight failures or the probability of failure are unpredictable.
Indeed, new scientific research will definitely have sacrifices, especially the scientific research results in the aerospace field, there must be a running-in process.
But such a research result is likely to be sacrificed, and the sacrifice may be the excellent pilots that some countries spend a lot of energy and money to cultivate.
There is a saying in the aviation field - a mature aircraft is run-in with the life of a pilot.
But this kind of risk cannot be taken by the institute, nor can the country take it.
Chen Xiao originally planned to say a few more words, but it is very likely that he informed these colleagues of the 606 Institute to study some key technologies of the engine.
In this way, they will be suspicious of Chen Xiao.
First of all, Chen Xiao studied finance, and secondly, even if Chen Xiao has made great achievements in science and technology, he is also engaged in the IC industry.
It can't be compared with the eight poles of the aerospace engine.
If you rashly inform the other party of these technologies, the follow-up explanation is quite troublesome.
Chen Xiao is the person who dislikes trouble the most.
And Chen Xiao also dislikes facing the media camera the most.
The researchers at the 606 Institute are all arrogant.
Because they are all elites in the country in the true sense, these technicians who can engage in aero-engine research and development are the elites among the elites.
Although many of them did not graduate from Yenching University or Shuimu University, the universities they graduated from, Bingcheng University of Technology, Western Regions University of Technology, Yenching Aviation, Aerospace University, etc. are no worse than Yenching University and Shuimu University. .
There used to be a joke in academia.
Shuimu University and Yenching University cultivate talents for foreign countries, while Bencheng University of Technology and National Defense University of Western Regions University of Technology cultivate talents for China.
At this time, several other employees of the 606 Institute said to Chen Xiao angrily: "Do you know how to solve these problems? Do you know that every time we modify a design detail, it costs a lot of money It is a very long and difficult process to re-experiment at the cost of it. It is not something that can be solved by just talking about it."
These employees did not know Chen Xiao, and thought that Chen Xiao was just an ordinary intensive care center staff member, and listened to their conversations.
After all, bragging is a matter of lip service, but in practice, it takes a lot of manpower and material resources.
An engine model goes from design to production to aerodynamic experiments, and finally all experiments are completed to form a complete data report.
Even if it is to modify some design parameters and re-experiment, it will take more than half a year. The human and financial resources spent are incalculable.
It is because of these hardships that the technicians of the 606 Institute will be very angry and directly attack Chen Xiao.
Because they think that Chen Xiao doesn't understand the difficulty of their work.
For example, the turbofan 10 engine was used in the wind tunnel laboratory in western Sichuan, where the conditions were extremely difficult, and even many excellent technicians were sacrificed because of the experiment.
The people of 606 Institute do not want their hard work and the products formed by paying the price with blood and life to be criticized by outsiders in this way.
Chen Xiao was not angry because of the impoliteness of these people, because Chen Xiao also does scientific research, and he quite understands the other party's mood.
At this time, Yao Ling, He Jiang's personal nurse, couldn't stand it any longer (nurses brought from 606 hospitals).
Yao Ling has been very tired during this time. Her eyes are red with bloodshot eyes. She knows that He Jiang can sit on the bed and talk at this time, thanks to Changtian Technology and Chen Xiao.
At this time, the technicians of the 606 Institute started to attack Chen Xiao frantically just because of a single engine and a technical battle of words. She definitely couldn't bear it.
If it weren't for Chen Xiao, He Jiang would not have been able to speak at all, how would he explain so many things today.
Yao Ling said: "This is President Chen of Changtian Technology."
Changtian Technology has only one President Chen, and that is Chen Xiao. The technicians of the 606 Institute immediately understood.
When Liu Dagen heard that it was Chen Xiao's name, he was very embarrassed.
He Jiang is his master, his teacher, and his leader.
On the way to Changzezhou, Liu Dagen heard that Changtian Technology used the business of hundreds of millions of meters in the Americas as a bargaining chip to force the American pharmaceutical giant to take medicine.
At such a high price, just taking medicine for a stranger, Liu Dagen was grateful, and said that if he could meet Chen Xiao, the head of Changtian Technology this time, he must kowtow to thank him.
He didn't expect that the person in front of him was Chen Xiao, and what he said just now was very offending.
Chen Xiao was not a person in the aviation engine industry, so there is no problem in making a few casual comments.
Liu Dagen hurriedly apologized and said, "Mr. Chen is really embarrassed. I was a little impulsive just now... Do you also know something about aero engines?"
Chen Xiao didn't get angry, but said with a smile: "I have had some exchanges with Professor He during this time, so I know some professional things."
"Firefly Technology Co., Ltd., a subsidiary of Changtian Technology, has been preparing a flight simulation game during this time. In order to make the game realistic, we also did some research on the engine, and added the corresponding parameters to the game. "
Chen Xiao said this, people including Liu Dagen are a little disdainful. How can aero-engine design be so difficult, so high-precision things can be solved with a game?
However, because of Chen Xiao's status and his life-saving grace to He Jiang, most of the people in the 606 Institute felt uncomfortable, but didn't express it.
Chen Xiao said: "He, everyone, have a good rest. After a while, I will let someone bring the corresponding software to you. You can take a look. Maybe it will be helpful for the research and development of the turbofan 10 engine."
Chen Xiao left the ward after leaving these words, and he already had some plans in his mind.
At present, Changtian Technology has advantages in ic and computer systems, especially after the successful development of Xiaoying Assistant, it uses advanced systems and Jiuzhang compiler software to complete the development of programs, which is extremely efficient.
The 100-ton thrust large engine is definitely helpful to protect Changtian Technology, otherwise the system will not light up such a technology tree at this time.
So what should Chen Xiao do?
You have the existing advantages of Changtian Technology, convert all the research and development instructions of the 100-ton thrust engine into algorithms, and install them in the research and development simulation software.
This software is loaded with the game as the skin.
There are two benefits to doing this.
The first is to be able to directly carry out the research and development of the engine. The computer simulation is faster than the real simulation and saves time.
The second is the ability to train engine R&D personnel at the fastest speed.
Through contact with the elites of the 606 Institute, it has been found that the country is currently lacking in engine research and development.
However, Chen Xiao believes that there are some mature underlying technologies that technicians do not need to understand, they can just learn and apply them directly.
Just like an excellent program engineer, you don't need to understand the development principles and machine code of C language or C++ at all, you only need to apply this language. Great writers don't need to understand how English or Chinese came from, they just need to understand the application of his consciousness.
The same should be true in the field of large aero-engine design, training applied talents rather than basic talents.
Of course, basic talents are very important, which is the foundation of all science, but their use is not in the engine research and development project of the 606 Institute, but in the breakthrough of new materials and new technologies.
Chen Xiao just had a simple idea, how the effect of the specific operation still needs to come up with the design software.
The Spring Festival is coming soon. In the fields of chip mobile phones and other fields, Chen Xiao is not worried at all, especially mobile phones will definitely exert force after the Spring Festival.
Taking advantage of the fact that the factories were shutting down one after another during this period, and everyone was going back for the Spring Festival, Chen Xiao decided to use the Jiuzhang compiler to make software first.
After Chen Xiao left the ward, the ward suddenly became lively.
The arrogance of intellectuals was displayed at once.
"We do thank Changtian Technology for treating Mr. He and Mr. He, but I don't quite agree with Mr. Chen's words just now."
"I don't agree either. I think President Chen has a deep understanding of aero engines, but he didn't come to our scientific research site in person. Solving the speed problem can solve the working problem of the engine. We can all understand these basic knowledge, but it is not that simple to solve these problems. Our engine is concentrated in a small space, and its lifespan must be guaranteed. !"
"It's just rhetoric!"
"A computer game also wants to simulate the process of designing an aircraft engine. How is that possible?"
Yao Ling couldn't listen any longer and said, "Do you know that when Chief He was delivered to Changzezhou that day, he almost stopped breathing. The medical staff of Changtian Technology Intensive Care Center tried their best to treat him. "
"Just a few days ago, Mr. He's lungs were seriously infected, and it was impossible to save them in any hospital in the country. It was also Changtian Technology. The medical staff of the intensive care center used superb technology to remove the lungs of the cooperation department. , and completed a sanction of the combined military, allowing He to save another life in total."
"We won't talk about the next thing~www.mtlnovel.com~ Get osimertinib and start targeted therapy, Mr. Chen is definitely not the kind of exaggerated person, I suggest you take a look at Mr. Chen's one Does the software help in the development of our turbofan 10 engine?"
Yao Ling felt it, but it is unknown how much the technicians of the 606 Institute could listen to.
At present, Yinghuo Technology, where Yang Fei is located, is still in Jiangzhou.
It happened that Chen Xiao was going back to Jiangzhou for the Spring Festival, so he came directly to Yinghuo Technology.
The first thing I did when I came to the company was to announce that Yinghuo Technology would not have a holiday during the Spring Festival, and asked Yang Fei to form a team to develop "new games" with Chen Xiao.
Changtian Technology's salary is generous, and the overtime pay is tripled during holidays. There is no problem at all. Therefore, everyone is not complaining about overtime, but excited.