Naruto: Katsumi

Katsumi Uchiha is the younger sister of Sasuke and Itachi Uchiha. She was forced to work under the likes of Orochimaru, along with fellow medic-nin, Kabuto. She had always regretted fleeing the Leaf, turning her back on her friends and mentors. What she also regretted was becoming attracted towards a certain male in which he felt something more, without the knowledge of her brother